Ionizable Lipids
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2025/09/18
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Polysciences’ Ionizable Lipids collection includes lipids such as DLin-MC3-DMA and DODAP that are neutral at physiological pH but become protonated in acidic environments. These lipids enable efficient nucleic acid encapsulation, endosomal release, and reduced cytotoxicity in lipid nanoparticle (LNP) formulations for mRNA, siRNA, and gene therapy applications.